Blood Group and Susceptibility to Diseases

April 7, 2011

Even recently it was considered that the life expectancy of the holders of O (I)blood group  is less than that of other blood groups, and generally, O- people are more prone to various diseases than for example, people of A-type. However, the latest statistical research undertaken by the European gerontologists shows that in modern Europe, the holders of A (II) blood group  rarely cross the line of 75-year life, as the A-type is the most susceptible to the so-called “diseases of civilization”-myocardial infarction, sclerosis, anemia, renal stone disease and diabetes.
Various adaptations of people with different phenotypes ABO are considered to be the result of screening mutagens. That is why there are hypothesis to explain the uneven distribution of ABO blood groups in the world  the influence of epidemics of infectious diseases such as plague, smallpox and cholera. As is known, the holders of the blood group O are vulnerable to cholera and the plague, as blood group A -to smallpox.
Immunologists explain this by the presence of some pathogens of antigens similar to antigens of human blood. So, the plague bacillus contains antigen-like antigen O, and the smallpox virus-antigen A. In such a way, the holders of the relevant blood groups are less resistant to cholera, smallpox or plague, because their immune system recognizes “the foreign” not immediately and react to them late or very poorly. That is why the blood group O practically does not occur in the population of India, North Africa, Mongolia and Turkey.
Statistical studies confirm that holders of blood group A get sick viral hepatitis more often, and O-type people are less resistant to influenza virus. According on the blood group, children under 7 years old usually get sick diseases such as paratyphoid fever, rubella, scarlet fever, colibacillosis, and among children with blood group A  it fails to develop immunity against smallpox even at re-vaccination.
Compared with the holders of three other blood groups O-adults dominate among the sufferers from duodenal ulcer, and among the children suffering from peptic ulcer disease, the prevalence of blood group O is not observed. Cases of acute appendicitis are the most frequent among the holders of blood group A , at the same time, among carriers of blood group AB it is fixed far more cases of appendicitis in the transition of peritonitis, besides, the AB-people are significantly more likely to be festering at all sorts of traumatic injuries.
Holders of blood group A  more often than others, suffer from cancer of the stomach, pancreas, salivary glands, ovaries and uterus. B-people are more prone to cancers of the esophagus and oral cavity, and the holders of blood group are at risk of tongue cancer, breast and lung.
It becomes apparent the decrease in the frequency of phenotype 0 and the increase the frequency of AB phenotype among  patients with osteochondrosis when analyzing the distribution of blood groups of patients with diseases of the musculoskeletal system.
Holders of blood group O are prone to respiratory diseases. On average, they often suffer from bronchial asthma and acute pneumonia than those in groups A, B , and AB . However, among children who have died of pneumonia and sepsis, as well as among infants with congenital malformations of the respiratory system are most frequently encountered groups  A and B.
During long-term observations it is found that the holders of blood groups O, A, B, and AB have different predisposition to diseases of the cardiovascular system. So among patients with atherosclerosis phenotype A is more common than phenotype O.
Furthermore, compared with other groups A-people are more susceptible to diseases of the cardiovascular system, mainly non-rheumatic origin. They are also more prone to coronary heart disease, compared, for example, with the owners of the blood group B. Among the holders of the blood group A there are frequent cases of embolism, thrombosis, myocardial infarction, which is quite unusual for group O. The same is true for hypertension, the most common among people of A-type and is extremely rare among the holders of the blood group AB.
According to many clinicians, the carriers of blood group B suffer from paralytic poliomyelitis far less frequently than other groups. Among  newborns with blood group O dystrophy develops much less frequently than among the holders of blood groups A, B, and AB. Among patients with diabetes are most often found representatives of the group A. With regard to skin-venereal diseases, compared with other blood groups A-type often suffers from skin diseases, and the ratio of syphilis B-people to O-people composes 1 to 5.
Study of blood groups continues, so do not be surprised of the above mutually exclusive information.


Ani is a 25 years old blogger, fond of music, sports and travelling. "Nothing under the sun is ever accidental." This is the slogan by which I am being guided.

  • M Noor

    Great site and information

    The diseases can be charted blood group type wise to make it easier to understand quickly

    God bless you

  • Rayford Cecchinato

    Thank you very much for the great content